Genetic Compatibility Test

Q: 2. Who is the Genetic Compatibility Test suitable for?

Couples with a family history of a genetic disease, either in one or both partners. Patients who are going to undergo assisted reproduction treatments and wish to reduce the risk of having a sick child. Patients who are going to undergo donation, whether it is an oocyte donation treatment or donor sperm. This test makes it possible to select the ideal donor and reduce the risk of having an affected child. In this way, we can guarantee that both donor and recipient do not share the same studied mutations. Couples who are consanguineous or closely related.

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Why take this compatibility test?

If you want to minimise the possibility of transmitting genetic diseases to your future child, the genetic compatibility test or genetic matching allows us to study hundreds of recessive or X-linked genetic diseases and check the probability of transmitting them to the embryo.

Do you want us to study your case?

The test can be performed on both partners or egg and sperm donors prior to pregnancy. The results enable you to make informed family planning decisions, in order to try to ensure the health of the future baby.

The importance of detecting recessive diseases

Recessive diseases are genetic disorders that occur when a person inherits two abnormal copies of the same gene, one from each parent. This means that the recessive disease only develops if the individual receives two copies of the altered gene, one from each parent. If both parents carry the same defective gene, the future baby has a 25% chance of developing the disease, a 50% chance of being a healthy carrier and a 25% chance of not inheriting any of the altered copies from its parents.

If only one of the parents is a carrier of the disease, the future baby inherits only one copy in 50% of the cases and usually has no symptoms.
Although these diseases are rare (affecting 1% of newborns), they are considered serious and incurable in many cases. Moreover, many of them begin to manifest themselves at birth or in infancy. Examples include cystic fibrosis and spinal muscular atrophy.

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We solve all your doubts

1. What does the Genetic Compatibility Test consist of?

The Genetic Compatibility Test, also known as Genetic Matching, uses a simple blood or saliva sample to study the DNA sequencing of both parents before pregnancy. It can be carried out on both members of a couple if they both provide their gametes, or on a donor who provides an egg and/or sperm and the other member of the couple, or between oocyte and sperm donors.

The results of the compatibility study usually take three to four weeks. In our centre, we study more than 300 recessive and X-linked diseases.

2. Who is the Genetic Compatibility Test suitable for?

Couples with a family history of a genetic disease, either in one or both partners.
Patients who are going to undergo assisted reproduction treatments and wish to reduce the risk of having a sick child.
Patients who are going to undergo donation, whether it is an oocyte donation treatment or donor sperm. This test makes it possible to select the ideal donor and reduce the risk of having an affected child. In this way, we can guarantee that both donor and recipient do not share the same studied mutations.
Couples who are consanguineous or closely related.

3. What to do if a genetic mutation is detected

If the Genetic Compatibility Test detects that one of the two members of the couple has a recessive genetic mutation, this does not carry any health risks for the carrier or the future baby.

However, if we discover that both parents (male and female) have a mutation of the same gene, there is a 25% chance that a child will be born with the disease.
In these cases, it is possible to act to eliminate this risk. To do this we have these options:

To perform an in vitro fertilisation treatment and, once the embryos have been obtained, we can carry out PGD (Preimplantation GeneticDiagnosis), i.e. we perform a biopsy of the embryo on day 5 or 6 of development to analyse it and thus be able to select and transfer only the embryos that have inherited a single copy (healthy carriers) or none at all.
Alternatively, we can use gamete donation, either egg or sperm that, again by means of the Genetic Compatibility Test, we can verify that the donor is compatible and does not have the same genetic mutation.

Your future baby is the most important thing

With a simple blood test, you can find out the risk of transmitting genetic diseases to your future baby

Why Tambre can fulfil your dream?

Especialistas en Medicina Reproductiva Avanzada

More advantages Tambre

A benchmark in technology and innovation in Reproductive Medicine

State-of-the-art assisted reproduction laboratory.
Our own andrology laboratory.

Latest technology

RI Witness™ for the safety and traceability of gametes.
GERI®: Embryo Incubator®.
Fenomatch, we find the right egg donor and/or sperm donor and match them with you.
Zymot-ICSI (Chip Fertile), selection of the best sperm before ICSI.

We support you and take care of you

We support you and take care of you with your own specialised medical unit. -You will have your own gynaecologist and nurse, except for emergencies, and the same medical team will follow your case in depth and attend you from the beginning to the end of the treatment.
You will have a consultant from our Specialised Tambre Care team who will support you and answer any question you may have throughout the whole process.